Management of Lobular Carcinoma In Situ and Atypical Lobular Hyperplasia Diagnosed by Core Biopsy
نویسندگان
چکیده
منابع مشابه
Most lobular carcinoma in situ and atypical lobular hyperplasia diagnosed on core needle biopsy can be managed clinically with radiologic follow-up in a multidisciplinary setting
We evaluated the efficacy of using standard radiologic and histologic criteria to guide the follow-up of patients with lobular carcinoma in situ (LCIS), lobular neoplasia (LN), or atypical lobular hyperplasia (ALH). Patients with high-risk benign lesions diagnosed on biopsy were presented and reviewed in a multidisciplinary clinical management conference from 1 November 2003 through September 2...
متن کاملIncidental minimal atypical lobular hyperplasia on core needle biopsy: correlation with findings on follow-up excision.
INTRODUCTION Atypical lobular hyperplasia (ALH), often an incidental finding in breast core biopsies, is largely considered to be a risk factor for carcinoma rather than a direct precursor. However, management of ALH is controversial. We review our experience with incidental minimal ALH on core biopsy, and correlate with excision and follow-up results. DESIGN We evaluated all cases of ALH on ...
متن کاملComparative genomic hybridization analysis of lobular carcinoma in situ and atypical lobular hyperplasia and potential roles for gains and losses of genetic material in breast neoplasia.
Lobular carcinoma in situ (LCIS) and atypical lobular hyperplasia (ALH) of the breast are cytologically similar breast lesions that reportedly carry different relative risks of subsequent development of invasive carcinoma. They are frequently multifocal and bilateral. We have identified the chromosomal copy number changes in 31 LCIS and 14 ALH lesions from 28 cases and also the 7 invasive carci...
متن کاملComparative Genomic Hybridization Analysis of Lobular Carcinoma in Situ and Atypical Lobular Hyperplasia and Potential Roles for Gains and Losses of Genetic Material in Breast Neoplasia1
Lobular carcinoma in situ (LCIS) and atypical lobular hyperplasia (ALH) of the breast are cytologically similar breast lesions that reportedly carry different relative risks of subsequent development of invasive car cinoma. They are frequently multifocal and bilateral. We have identified the chromosomal copy number changes in 31 LCIS and 14 ALH lesions from 28 cases and also the 7 invasive carc...
متن کاملClonality of lobular carcinoma in situ and synchronous invasive lobular carcinoma.
BACKGROUND Lobular carcinoma in situ (LCIS) of the breast is considered a marker for an increased risk of carcinoma in both breasts. However, the frequent association of LCIS with invasive lobular carcinoma (ILC) suggests a precursor-product relation. The possible genomic relation between synchronous LCIS and ILC was analyzed using the technique of array-based comparative genomic hybridization ...
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ژورنال
عنوان ژورنال: American Journal of Clinical Pathology
سال: 2012
ISSN: 0002-9173,1943-7722
DOI: 10.1093/ajcp/138.suppl1.077